Schizophrenia is a disabling, lifelong disease that is difficult to diagnose and treat due to its complexities and challenges. These same intricacies and complications are a critical part of clinical trial development that require a deep understanding of the disease and how to mitigate the anticipated challenges during trial design necessary to advance treatment without delaying study timelines.

In this article, we discuss how to overcome three of the most complex challenges of any Schizophrenia trial:

• • Assessments and Scales
  • Raters and Site Management
  • Recruitment and Retention