Pain Research
Advancing pain research with smarter clinical trials
He didn’t just need a CRO. He needed
an ally. That’s when we stepped up.
The Pain Perception Puzzle:
Measuring What Matters in Pain Trials
Acute and chronic pain conditions affect millions, making pain research a critical area for innovation. At Rho, we approach pain clinical trials with a deep understanding of the complexities of pain assessment, treatment efficacy, and regulatory expectations. Our team works closely with sponsors to design studies that lead to meaningful outcomes, ensuring that new treatments are both effective and accessible to patients who need them most.
Why Rho?
Why Rho?
Extensive pain research expertise
Innovative trial design
Regulatory leadership
Patient-focused strategies
Spotlight: Advancing Complex Pain Studies with Expertise and Agility
Rho’s deep expertise in pain research shines through in both chronic and acute studies. In a recent chronic pain study, our team enrolled more than 200 subjects with diabetic peripheral neuropathy across 31 U.S. sites. We overcame challenges like site inexperience with electronic diaries and complex inclusion/exclusion criteria by delivering tailored training, close monitoring, and proactive issue resolution. This attention to detail helped ensure high-quality data in a difficult-to-enroll population.
In an acute pain trial supporting an NDA, we activated 44 U.S. sites and randomized nearly 500 subjects undergoing bunionectomy surgery. Our proactive site engagement, real-time support, and focus on operational efficiency enabled us to complete enrollment within six months—well ahead of sponsor expectations.
Whether the challenge is chronic neuropathic pain or post-surgical pain, our collaborative, solutions-oriented approach consistently drives results.
Rho’s deep expertise in pain research shines through in both chronic and acute studies. In a recent chronic pain study, our team enrolled more than 200 subjects with diabetic peripheral neuropathy across 31 U.S. sites. We overcame challenges like site inexperience with electronic diaries and complex inclusion/exclusion criteria by delivering tailored training, close monitoring, and proactive issue resolution. This attention to detail helped ensure high-quality data in a difficult-to-enroll population.
In an acute pain trial supporting an NDA, we activated 44 U.S. sites and randomized nearly 500 subjects undergoing bunionectomy surgery. Our proactive site engagement, real-time support, and focus on operational efficiency enabled us to complete enrollment within six months—well ahead of sponsor expectations.
Whether the challenge is chronic neuropathic pain or post-surgical pain, our collaborative, solutions-oriented approach consistently drives results.
Spotlight: Advancing Complex Pain Studies with Expertise and Agility
Rho’s deep expertise in pain research shines through in both chronic and acute studies. In a recent chronic pain study, our team enrolled more than 200 subjects with diabetic peripheral neuropathy across 31 U.S. sites. We overcame challenges like site inexperience with electronic diaries and complex inclusion/exclusion criteria by delivering tailored training, close monitoring, and proactive issue resolution. This attention to detail helped ensure high-quality data in a difficult-to-enroll population.
In an acute pain trial supporting an NDA, we activated 44 U.S. sites and randomized nearly 500 subjects undergoing bunionectomy surgery. Our proactive site engagement, real-time support, and focus on operational efficiency enabled us to complete enrollment within six months—well ahead of sponsor expectations.
Whether the challenge is chronic neuropathic pain or post-surgical pain, our collaborative, solutions-oriented approach consistently drives results.
Rho’s deep expertise in pain research shines through in both chronic and acute studies. In a recent chronic pain study, our team enrolled more than 200 subjects with diabetic peripheral neuropathy across 31 U.S. sites. We overcame challenges like site inexperience with electronic diaries and complex inclusion/exclusion criteria by delivering tailored training, close monitoring, and proactive issue resolution. This attention to detail helped ensure high-quality data in a difficult-to-enroll population.
In an acute pain trial supporting an NDA, we activated 44 U.S. sites and randomized nearly 500 subjects undergoing bunionectomy surgery. Our proactive site engagement, real-time support, and focus on operational efficiency enabled us to complete enrollment within six months—well ahead of sponsor expectations.
Whether the challenge is chronic neuropathic pain or post-surgical pain, our collaborative, solutions-oriented approach consistently drives results.
Pain FAQ
What pain management conditions does Rho specialize in?
Rho supports trials for post-operative, acute, chronic, and neuropathic pain, including models in dental pain, bunionectomy, and abdominoplasty.
What are the challenges of pain clinical trials?
Pain trials often involve subjective endpoints, placebo effects, and regulatory scrutiny around analgesics. Rho’s experience ensures trial designs are rigorous, endpoints are validated, and data is compelling for regulatory submission.
How does Rho address placebo challenges in pain trials?
Rho employs innovative methodologies, such as enriched enrollment designs and tailored patient-reported outcomes, to minimize placebo effects and enhance data quality in pain studies.
Does Rho offer expertise in non-opioid pain therapies?
Rho has significant experience in non-opioid pain trials, supporting the development of safer and effective alternatives. Our integrated teams ensure efficient trial execution and clear regulatory pathways.
Comprehensive support for pain
clinical trials
We provide full-service support across all phases of pain research:
Chronic pain studies
Neuropathic pain research
Post-operative and acute pain trials
Patient-centered methodologies
Regulatory strategy and controlled substance guidance
Site relationships
Meet the
team
who make
it happen
Related insights & resources
Ready to move pain research forward?
Better pain treatments start with better trials. Let’s build a study designed for real impact.
